A European multidisciplinary network for the fight of HIV drug resistance
On Feb 4th, our great friend and EuResister Andrea De Luca lost his life in a horrible car accident, at the age of 55. Among many other projects, Andrea joined EuResist as a key leader soon after its launch, devoting his energy, commitment and capability to the success of the Network. He was an extra lively, smart, passionate, and positive person, always ready to help and take new tasks. He will be deeply missed by both his colleagues and his patients.
We send a big hug to him for the new journey and our condolences to his family and loved ones.
PhD fellowship on HIV molecular epidemiology
A PhD fellowship on HIV molecular epidemiology has been funded by the EuResist Network at the PhD programme in Data Science of Sapienza University of Rome. The PhD in Data Science of Sapienza is a multidisciplinary doctoral program coordinated by the Department of Computer, Control and Management Engineering "Antonio Ruberti".
The student supported by the fellowship, who has already been selected, will focus on epidemiology of subtype A in the EuResist Integrated DataBase.
The CARE project starts publishing its first results
In only ten months of activity the CARE partners created a solid ethics permissions, data and samples sharing infrastructure for a wide network of collaboration against HIV, TB and HCV. Already three papers have been published on HIV-1 resistance and epidemiology and the poster "HIV-1 A6 Subtype: its challenging identification and Southern Russian molecular epidemiology" (S. Sierra et al.) will be presented at EACS 2019!
The CARE project receives funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 825673.
Data from over 103, 000 HIV patients in EIDB
The EIDB, expanded to collect clinical and resistance information, contains now data from over 103, 000 HIV patients, The DB is always available for HIV research studies, subject to approval by the Scientific Board. If you are interested to submit a study please contact us.
Two posters from the EuResist Mentor School to be presented at EACS 2019
The two studies: “A retrospective analysis of the EuResist data set assessing dual therapy success in a real-life context” and “A retrospective analysis of the EuResist data set assessing if NRTI resistance impairs INSTI based treatment with NRTI backbone” have been realized by the participants of the EMS 2018 under guidance of the trainer M. Bohm and of EuResist Network mentors.
The project has been supported by Janssen Parmaceutical and Gilead Sciences.
INTEGRATE at EACS 2019
The INTEGRATE project results will be presented at. EACS 2019, to be held in Basel on November 6-9 2019, with an oral talk entitled "Prevalence of InSTI resistance and effectiveness of InSTI based regimens in HIV infected patients: results from a European cohort" (B. Brossetti et al.). The presentation will take place on Thursday, November 7th 2019 during the session "Basic and translational HIV biology" (14:00-16:00).
The project has been supported by an unrestricted grant from Gilead Sciences.
EuResist at the PROHIV 2019 international conference on HIV and AIDS, Moscow 23-24 September 2019
EuResist will be present with a talk entitled "The EuResist Integrated DataBase: how to exploit real life data for the study of HIV drug resistance" at the PROHIV 2019 international conference on HIV and AIDS to be held in Moscow on September 23-24 2019.
Two abstracts from the EMS at the 17th European Meeting on HIV & Hepatitis May 2019
Two studies realised by the students of the EuResist Mentor School under the guidance of the tutors will be presented as posters at the European HIV & Hep Meeting in Rome 22-24 May 2019.
EuResist at the AREVIR meeting 3-4 May 2019
EuResist recent results will be presented in the EuResist session within the annual AREVIR meeting in Cologne 3-4 May 2019.
The CARE project breakes the news
Read it on Il Sole 24 ore sanità!
CARE project kick-off meeting 23-24 January
The CARE project kick-off meeting will be in Rome on 23-24 January
Abstract on INTEGRATE dataset accepted at CROI 2019
The study on "GSS of NRTI-backbone predicts time to virological failure of InSTIs-based regimens" realised on INTEGRATE data has been accepted for poster presentation at CROI 2019
in Seattle 4-7 March 2019.
CARE project accepted for funding by the EC under the topic H2020-SC1-BHC-21-2018 of the H2020 programme
CARE is a COMMON ACTION AGAINST HIV/TB/HCV ACROSS THE REGIONS OF EUROPE, coordinated by EuResist Network with scientific coordination of CHIP/RegionH
About EuResist Network
EuResist Network is an international non-profit partnership devoted to understanding and fighting the resistance to anti-HIV drugs.
Its approach is eminentely multidisciplinary and focused on exploiting the power of real world data at the benefit of the individual patient.
EuResist Network manages:
the EuResist Integrated Data Base (EIDB), among the largest available databases of HIV genotypes and clinical response to antiretroviral therapy, with more than 96.000 patients. The EIDB is open for research studies.
Reasearch projects on HIV and other infectious diseases.. EuResist Network is actively involved in front end research to combat HIV drug resistance and the spread of HIV and other infectious diseases. It coordinates and participates in several research projects, including EU funded projects.
Training activities on HIV drug resistance and data management. EuResist Network organises on-site and distant courses and offers training material on drug resistance and drug resistance data management.
The EuResist prediction engine, a data-driven system which predicts the response to combination drug therapy for a patient with a given viral genotype. The engine has an overall accuracy of around 77% which compares favourably with existing rules-based state-of-the-art systems such as HIVdb, ANRS, REGA.
The EuResist Satellite DB (EsaDB), a tool for management of HIV patients data running locally on a PC. ESaDB is provided for free.
CARE (Common Action against HIV/TB/HCV across the Regions of Europe) aims at analysing and addressing the human immunodeficiency virus (HIV), tuberculosis (TB) and hepatitis C (HCV) epidemics across Europe and Russia, by establishing new networks and consolidating previous cooperative actions between the European Union and the Russian Federation.
Project coordinator F. Incardona (EuResist Network) Scientific coordinator J. Lundgren (CHIP/RegionH).
Funding received from the EU’s H2020 research and innovation programme under g.a N. 825673
The INTEGRATE project aims at building and maintaining a large, curated collection of virological and clinical data to increase scientific knowledge on resistance to integrase strand transfer inhibitors (InSTI) and on the most appropriate use of this class of antiretroviral agents.
EuResist Network organises the EuResist Mentor School (EMS) an innovative educational project finalised to train young physicians and biologists in dealing with structured data (databases).
The EMS 2018 has been successfully held in Cologne
The EuResist Network is open to new partners of proved or potential scientific value for expanding both database and scientific programme. Co-operation with developing countries with high rates of HIV infections is mostly welcome.
All the partners have one representative in the EuResist Network Scientific Board. The Board evaluates requests to access the EIDB for scientific studies. Partner's activities and data are protected by the data and authorship policy.